Chapter 1

2 Timothy 1:6-7 - Timidity conceals the gifts. Concealing gifts causes them to be extinguished. By contrast, when we exercise our gifts, they grow and fan to flame. Paul imparted gifts to Timothy by laying on of hands and prayer (implied).

2 Timothy 1:8 - Paul isn't saying that Timothy shouldn't be ashamed of the Lord Jesus personally, but rather that he shouldn't be ashamed of what he has to say about the Lord Jesus. Probably, since Timothy was living among the Greeks, it would have been difficult to talk about Jesus being the one and only sin bearer and that He rose from the dead. Those are two things that would starkly clash with Greek religion at the time (what we now call Greek Mythology).

2 Timothy 1:9 - When Paul is speaking of "holy calling" here, he is not referring to the call for salvation. Salvation is referenced in part of this verse. This calling is the call to ministry. Thus the call to ministry is not in reference to our works or capacities. It is according to God's own purpose and grace.

2 Timothy 1:10 - All souls are immortal. In the language of the Bible, however, hell is spoken of as the second death. Thus, heaven is the alternative to death, which is immortality. Paul adds, according to Calvin, the descriptor of "immortality" in this verse to be more specific about the "life" Jesus brings to light.

2 Timothy 1:12 - Keys to an effective Christian life - (1) Know whom you are trusting. Not just the name or concept, but really know Him. (2) Be persuaded of His power. He was resurrected, did miracles, and ascended into Heaven. (3) Entrust your life to Him. The ESV reads this as "what has been entrusted to me", but I don't think the Greek actually reads that way. It seems to me that Paul is talking about something that he has entrusted to the Lord. It doesn't make sense in context to say that God will keep what was entrusted to Paul. (4) Be willing to suffer hardship for Him.

2 Timothy 1:13-14 - Paul ends this passage with two admonitions: Follow my pattern and guard the deposit. The former is in reference to the outward or conduct, such as enduring suffering and perseverance. The latter is inward, spiritual deposit or gifts (see vs. 6).